中枢神经系统试验影像：

作为神经放射学、肌肉骨骼放射学和介入放射学方面的一位知名专家，Stephen 为凯理斯带来了逾 30 年的广泛经验。其专业知识来源于在备受赞誉的医疗保健中心担任经委员会认证的放射科诊断医生、在顶尖学术机构担任高级教员，以及在众多全球制药公司担任值得信赖的科学顾问。

In his present role as Neurology Therapeutic Lead, Dr. Rohit Sood has contributed as a scientific lead on over 160 imaging clinical trials spanning the entire spectrum, from early to late phase, across multiple therapeutic areas including more than 40 in neurological indications. He has contributed to the science on several Neuro-oncology, Neurodegenerative, Neuropsychiatry and Rare disease clinical trials and has collaborated with our study sponsors to develop criteria for evaluating the eligibility, efficacy, and safety aspects of their studies. As a senior member of several scientific organizations and societies, Dr. Sood is actively engaged in furthering the science in the clinical trial space.

Manuela is responsible for providing scientific advice on implementing medical imaging into clinical trials, conducting investigator, internal staff, and independent reviewer trainings, supporting the development of independent review charters, providing guidance to R&D and application development in the customization of image analysis software tools, and monitoring independent reviewer performance. Manuela has significant experience in leading and managing the imaging component of multiple neurology and oncology clinical trials, with expertise in applying neuro-oncology image assessment criteria such as RANO, iRANO, LANO, REiNS and volumetric analysis.

As a Senior Scientist at Calyx, Alice Motovylyak leverages her extensive knowledge in CNS disorders, including Alzheimer’s disease and spinal cord injury, as she designs and implements workflows for clinical trials involving imaging-based endpoints in these areas. To this end, she is involved in all study-related aspects including image acquisition, review design, development of independent reviewer charters, analysis application development, and independent reviewer training. Prior to joining Calyx, Alice was a post-doctoral researcher at the Alzheimer’s Disease Research Center (ADRC) at the University of Wisconsin where she focused on imaging biomarkers of aging and understanding how aging and risk factors of Alzheimer’s disease influence brain structure using diffusion weighted imaging.